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Podcasts


2015

 Pain and the Brain: Using Patient-Derived Neurons for Preclinical Phenotypic Screening
with Elizabeth D. Buttermore, Ph.D., Research Fellow, F.M. Kirby Neurobiology Center, Boston Children's Hospital; Neurobiology Department, Harvard Medical School
 

 Tissue Stem Cells, Tumors, Toxicity and Time
with James L. Sherley, M.D., Ph.D., Director, Asymmetrex, LLC
 

2014

 Chemical Route Development of HCV Protease-Inhibitor, Telaprevir
with Dr. Gerald Tanoury
 

 How HIGH Can You Get? Using in vitro Data to Reduce Animal Experiments & Enabling Forms in Discovery-Development Interface
with Dr. Geeti Gangal
 

 Development of Poorly Soluble Drug: Current and Future Perspectives on Dissolution Prediction and Experimentation
with Robert A. Bellantone, Ph.D.
 

 Exploring and Optimizing Cost-Effective Route toward DPP-IV Inhibitor Compounds
with Nhut Diep, Ph.D.
 





Videos

Dr. Renato Skerlj, founder of Drug Discovery Consulting LLC and former Head of Small Molecule Discovery at Genzyme, and CHI's Dr. Edel O'Regan, discuss hot topics in medicinal chemistry including: residence time, covalent inhibition, beyond the rule-of-five, protein-protein interactions, macrocycles. 






Dr. Stewart Fisher, Principal at SL Fisher Consulting and former Executive Director at AstraZeneca, discusses allosteric inhibition, natural product chemistries, covalent inhibition strategies and binding kinetics in drug discovery. 









In part two of his conference preview, Dr. Fisher discusses the importance of receptor binding kinetics and the role of residence time. 













Archives


2013

Technological Advances in Preclinical Imaging: What to Expect with Erik M. Shapiro, Ph.D. 


2012

Alzheimer’s Targets and the Path to the Clinic with Dennis Selkoe and Corinne Augelli-Szafran 


2011

Preclinical and Clinical Update with Keynote Speaker, Kuldip Dave from the MJFF